BindCraft

by FreedomIntelligence

BindCraft is an AI Engineering skill for Claude Code, published by FreedomIntelligence in OpenClaw-Medical-Skills.

2.9K stars410 forkson FreedomIntelligence/OpenClaw-Medical-SkillsAdded 2026/08/17Repository updated 2026/07/21

View source on GitHub Download repo ZIP

awesomeclaude-codeclawhubmedicalnanoclawopenclawopenclaw-skillsskills

Install in seconds

Install BindCraft

Copy BindCraft into your Claude Code skills folder. Run the command in your terminal, or review the source on GitHub before installing.

terminal

npx degit https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bindcraft ~/.claude/skills/bindcraft

Requires Node.js. Downloads this skill only — not the rest of the repository — into your Claude Code skills folder.

Without Node.js

git clone https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git

Clones the whole repository, then copy the skill’s own directory into your skills folder yourself.

In this catalog

Source file: skills/bindcraft/SKILL.md in FreedomIntelligence/OpenClaw-Medical-Skills
Installs to: ~/.claude/skills/bindcraft
Collection: One of 25 skills cataloged from this repository
Category: AI Engineering — 2451 skills

What BindCraft does

BindCraft designs protein binders using end-to-end optimization with built-in AF2 validation. Use it for production-quality binder campaigns with joint backbone and sequence optimization.

BindCraft is cataloged under AI Engineering on DirSkills. BindCraft comes from a repository tagged awesome, claude-code, clawhub, medical and nanoclaw.

Documentation

README

Excerpt

BindCraft Binder Design

Prerequisites

Requirement	Minimum	Recommended
Python	3.9+	3.10
CUDA	11.7+	12.0+
GPU VRAM	32GB	48GB (L40S)
RAM	32GB	64GB

How to run

First time? See Installation Guide to set up Modal and biomodals.

cd biomodals
modal run modal_bindcraft.py \
  --target-pdb target.pdb \
  --target-chain A \
  --binder-lengths 70-100 \
  --hotspots "A45,A67,A89" \
  --num-designs 50

GPU: L40S (48GB) | Timeout: 3600s default

This is the opening of the README. Read the full README on GitHub.

Frequently asked about BindCraft

What else does FreedomIntelligence publish alongside BindCraft?
BindCraft is one of 25 skills that DirSkills catalogs from FreedomIntelligence/OpenClaw-Medical-Skills, the repository it ships in. Its siblings there include AAV Vector Design Agent, ADHD Daily Planner and ADMET Prediction. Each one is a separate skill with its own page in this directory, installs the same way BindCraft does, and is maintained by FreedomIntelligence in that same repository. The rest of the collection is listed on the FreedomIntelligence/OpenClaw-Medical-Skills page.
How does BindCraft compare to other AI Engineering skills?
BindCraft ranks #695 by stars among the 2451 AI Engineering skills in this catalog. The most-starred ones next to it are Architecture Decision Records, AI-First Engineering and Agentic OS. DirSkills ranks by the star count of the repository each skill ships in, so that order reflects how popular those repositories are rather than any review of BindCraft against them. Open each page to compare what they document and how they install.