Boltz

Boltz is an AI Engineering skill for Claude Code, published by BioTender-max in awesome-bio-agent-skills.

174 stars30 forkson BioTender-max/awesome-bio-agent-skillsAdded 2026/09/07+1% in starsRepository updated 2026/07/01

agent-skillsai-agentai-agentsawesomeawesome-listbioinformaticsbiomedicalclaudeclaude-codeclaude-skillscomputational-biologydrug-discoverygenomicsllmmcpprotein-designproteomicssingle-cellskillstranscriptomics

Install in seconds

Install Boltz

Copy Boltz into your Claude Code skills folder. Run the command in your terminal, or review the source on GitHub before installing.

terminal

npx degit https://github.com/BioTender-max/awesome-bio-agent-skills/tree/main/skills/adaptyv/boltz ~/.claude/skills/boltz

Requires Node.js. Downloads this skill only — not the rest of the repository — into your Claude Code skills folder.

Without Node.js

git clone https://github.com/BioTender-max/awesome-bio-agent-skills.git

Clones the whole repository, then copy the skill’s own directory into your skills folder yourself.

In this catalog

Source file: skills/adaptyv/boltz/SKILL.md in BioTender-max/awesome-bio-agent-skills
Installs to: ~/.claude/skills/boltz
Collection: One of 25 skills cataloged from this repository
Category: AI Engineering — 3475 skills

What Boltz does

Boltz predicts protein complexes, protein-ligand complexes, and other biomolecular structures with Boltz-1/Boltz-2. Use it for binder validation or open-source structure prediction on local GPU resources.

Boltz is cataloged under AI Engineering on DirSkills. Boltz comes from a repository tagged agent-skills, ai-agent, ai-agents, awesome and awesome-list.

Documentation

README

Excerpt

Boltz Structure Prediction

Prerequisites

Requirement	Minimum	Recommended
Python	3.10+	3.11
CUDA	12.0+	12.1+
GPU VRAM	24GB	48GB (L40S)
RAM	32GB	64GB

How to run

First time? See Installation Guide to set up Modal and biomodals.

cd biomodals
modal run modal_boltz.py \
  --input-faa complex.fasta \
  --out-dir predictions/

GPU: L40S (48GB) | Timeout: 1800s default

Option 2: Local installation

pip install boltz

boltz predict \
  --fasta complex.fasta \
  --output predictions/

Key parameters

This is the opening of the README. Read the full README on GitHub.

Frequently asked about Boltz

What else does BioTender-max publish alongside Boltz?
Boltz is one of 25 skills that DirSkills catalogs from BioTender-max/awesome-bio-agent-skills, the repository it ships in. Its siblings there include ATAC Seq, AlphaFold and BindCraft Binder Design. Each one is a separate skill with its own page in this directory, installs the same way Boltz does, and is maintained by BioTender-max in that same repository. The rest of the collection is listed on the BioTender-max/awesome-bio-agent-skills page.
How does Boltz compare to other AI Engineering skills?
Boltz ranks #3210 by stars among the 3475 AI Engineering skills in this catalog. The most-starred ones next to it are Architecture Decision Records, AI-First Engineering and Agentic OS. DirSkills ranks by the star count of the repository each skill ships in, so that order reflects how popular those repositories are rather than any review of Boltz against them. Open each page to compare what they document and how they install.