AI Engineering

AlphaFold validates protein designs with structure prediction for single chains and complexes. Use it to check folding, predict binder-target interfaces, and review confidence metrics like pLDDT, pTM, and ipTM.

API Design helps design production-quality RESTful APIs with resource modeling, HTTP methods, status codes, pagination, versioning, and OpenAPI docs. Use it when you need endpoint definitions, schemas, or a REST API specification.

API Integration builds reliable clients for external APIs using REST, webhooks, polling, or SDK wrappers. It handles authentication, rate limits, retries, and error handling when you need production-ready integration code.

BindCraft Binder Design generates protein binders with built-in AlphaFold2 validation and joint backbone/sequence optimization. Use it for production binder campaigns and protocol choices like fast, default, or slow.

Binder Design helps choose between BoltzGen, BindCraft, RFdiffusion, and related tools for protein binder projects. Use it to plan a binder design campaign, compare trade-offs, and pick a workflow for the target type.

Binding Characterization guides SPR and BLI assay planning, troubleshooting, and kinetic data interpretation. Use it when choosing a platform, diagnosing weak or noisy binding, or handling mass transport and regeneration issues.

Bio Agent Skills Hub routes biomedical and bioinformatics requests to the best matching Claude Code skill by searching an index of 1,676 skills, fetching the selected SKILL.md, and following its instructions. Use it for genomics, transcriptomics, single-cell, proteomics, clinical, and multi-omics tasks.

Bio Analysis System designs the analysis layer of a manuscript by mapping figures and tasks to quantitative, qualitative, and biological analyses. Use it to choose methods, tools, and claims for related-work-driven paper planning.

Boltz predicts protein complexes, protein-ligand complexes, and other biomolecular structures with Boltz-1/Boltz-2. Use it for binder validation or open-source structure prediction on local GPU resources.

BoltzGen designs all-atom protein binders and peptides with YAML-configured diffusion. Use it for side-chain aware designs, small-molecule binding, or precise interface geometry; use RFdiffusion for backbone-only work.

Campaign Manager turns binder design goals into runnable pipelines and estimates designs, time, cost, and expected yield. It is used to assess campaign health, diagnose QC failures, and choose among protein design tools.

Cell-Free Expression gives guidance for optimizing cell-free protein synthesis experiments, including template design, yield troubleshooting, and folding difficult proteins. Use it when planning CFPS runs or diagnosing low expression, aggregation, or disulfide issues.